Bylvay Patient Support & Resources – Bylvay™ (odevixibat)

Support and Resources for Families Living with PFIC

Albireo Assist is a patient support program for people taking Bylvay and their caregivers.

People who are prescribed Bylvay and their caregivers can enroll in Albireo Assist. Once enrolled, they are assigned dedicated Care Coordinators who are available throughout their treatment journey. Care Coordinators can provide:

Financial & Insurance Assistance

The goal of Albireo Assist is to help make Bylvay treatment affordable and available to those who have been prescribed it. Your Albireo Assist Care Coordinator can help make obtaining Bylvay easier for you by evaluating your health insurance and helping with the coverage process.

Your Care Coordinator can evaluate your benefits, deductibles, and copay or coinsurance, and can help secure the paperwork used by insurance companies to determine whether they will cover the cost of a prescribed medicine (known as prior authorization), as well as helping with any other requirements.

We know that paying for treatment can sometimes be a challenge. There may be financial assistance programs available to you. Once you are signed up with Albireo Assist, you will be automatically enrolled in the financial assistance programs for which you may be eligible. Your dedicated Care Coordinator can help you understand your insurance and coverage options, and which programs you might be eligible for.

Albireo Assists’ $0 Copay Assistance Program*

Even with insurance, affording prescription medication can be difficult. If you qualify, your Care Coordinator can help you enroll in the Copay Assistance Program, which can help you get your Bylvay medication with less out-of-pocket cost. This option, which could bring your copay to as little as $0, is available for some people who have commercial or private health insurance and meet the eligibility requirements.*

*This Copay Program is not valid for prescriptions that are eligible to be reimbursed, in whole or in part, by Medicaid, Medicare (including Part D), Medigap, VA, DoD, Tricare or other federal or state healthcare programs (including any state prescription drug assistance programs). The Program is not valid for prescriptions that are eligible to be reimbursed by private insurance plans or other health or pharmacy benefit programs which reimburse you for the entire cost of your prescription drugs. Benefits payable under this program may not exceed the annual maximum permitted by Program rules. Contact 855-252-4736 for details. Find a link to the full TERMS AND CONDITIONS below.

Learn more about the Copay Assistance Program from your Care Coordinator.

Patient Assistance Program

The Patient Assistance Program can provide free drug to patients with financial need. This program is available to eligible patients who qualify based on income and other financial factors. Your Care Coordinator can discuss with you if you are eligible for this program.

Learn more about the Patient Assistance Program from your Care Coordinator.

Not sure which financial assistance programs may be able to help you?
Your Albireo Assist Care Coordinator can help by walking you through options based on your individual situation. Just give us a call at 855-ALBIREO (855-252-4736), 8am-6pm ET, or contact your Care Coordinator directly.

Dedicated, Live Support

When you enroll in Albireo Assist, you will be contacted by your Care Coordinator, who will be your primary contact with the program. Your Care Coordinator has training and experience with the healthcare system and with rare diseases, so they understand the challenges you may be facing.

Your Care Coordinator is regionally based and is fully dedicated to your case and to helping you along this journey. Most importantly, they are experienced professionals who are ready to help with personalized support based on your situation.

Here are just a few of the kinds of issues your Care Coordinator can help with:

Questions about your health insurance coverage for Bylvay
Helping handle some of the details and paperwork involved with getting the medication covered by insurance
Information about financial assistance programs that may be available
Getting information about the next refill or other information from the specialty pharmacy who handles the prescription
Making sure the specialty pharmacy knows where to send the medication
Providing information on support groups, community resources, and patient meetings

If you have questions, let us know and we'll help get some answers. Your Care Coordinator is just a phone call or email away. Call 855-ALBIREO (855-252-4736) or contact your Care Coordinator at their direct number or email address.

Care Logistics

Bylvay is available only through Albireo Assist specialty pharmacy partners. Your Care Coordinator will connect you to a specialty pharmacy who will fill the prescription each month and deliver it directly to you—even if you are traveling or moving.

Situations change and we’re here to help navigate those changes so that they don’t have an impact on treatment. If you change jobs, change doctors, change insurance, or change locations, just let us know—we’ll work to help make sure that these changes don’t affect getting the medication.

Your Care Coordinator is here to help with those kinds of logistics. Call 855-ALBIREO (855-252-4736) or contact your Care Coordinator at their direct number or email address.

Educational Materials & Programs

In addition to all the services that are part of Albireo Assist, we also offer educational and support resources for patients and their families. These include informative, downloadable materials, as well as links to patient organizations and community groups. The Resources page has the details and the downloads.

We're here to help answer your questions or to point you to resources that can help.

Click here for full terms and conditions

Online Resources

PFIC Advocacy and Resource Network aims to improve the lives of patients and families worldwide affected by PFIC
Visit now ❯
National Organization for Rare Disorders (NORD) is a patient advocacy organization dedicated to individuals with rare diseases and the organizations that serve them. It is committed to the identification, treatment, and cure of rare disorders through programs of education, advocacy, research, and patient services
Visit now ❯
American Liver Foundation (ALF) is a national, voluntary nonprofit organization dedicated to the prevention, treatment, and cure of hepatitis and other liver diseases through research, education, and advocacy
Visit now ❯
Children's Liver Disease Research Network (ChiLDReN) offers medical and patient advocacy support with clinical sites and research labs in the U.S.
Visit now ❯
Children's Liver Disease Foundation (CLDF) is a UK-based charity dedicated to pediatric liver diseases
Visit now ❯

Additional Resources

Patient Brochure English

Patient Brochure Spanish

Bylvay Instructions for Use Videos

See How Bylvay Oral Pellets are Opened and Sprinkled

Watch this brief instructional video for a demonstration on how to open Bylvay Oral Pellets and mix them with a small amount of soft food.

See How Bylvay Oral Pellets are Opened and Mixed with Liquid

Watch this brief instructional video for a demonstration on how to open Bylvay Oral Pellets and mix them with liquid.

IMPORTANT SAFETY INFORMATION AND INDICATIONS

IMPORTANT SAFETY INFORMATION

Speak with your healthcare provider if you experience abdominal pain, vomiting, diarrhea, hematoma, decreased weight, or dehydration as these have been reported with the use of Bylvay. Patients should contact their healthcare provider if they experience new onset or worsening of diarrhea
Elevations in liver tests (for example, AST, ALT, TB) have been observed with use of Bylvay. The patient’s healthcare provider will obtain liver tests before starting Bylvay and periodically during treatment with Bylvay. Patients should report to their healthcare provider any symptoms of liver problems (for example, nausea, vomiting, skin or the whites of eyes turn yellow, dark or brown urine, pain on the right side of the abdomen, loss of appetite)
Bylvay may impair absorption of fat-soluble vitamins (FSV), which include vitamins A, D, E and K (vitamin K is assessed by measuring INR). The patient’s healthcare provider will obtain serum levels of vitamins A, D, E, and INR (for vitamin K) at baseline and periodically during treatment to assess for worsening of FSV deficiency
Do not swallow the 200 mcg or 600 mcg capsule(s) containing Oral Pellets whole. These are intended to be opened and the contents mixed into soft food. Take Bylvay in the morning with a meal
For patients taking bile acid binding resins, take Bylvay at least 4 hours before or 4 hours after taking a bile acid binding resin
There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to Bylvay during pregnancy. For more information, please call 1-855-252-4736

Indications and Usage

Bylvay is an ileal bile acid transporter (IBAT) inhibitor indicated for the treatment of cholestatic pruritus in:

Patients 12 months of age and older with Alagille syndrome (ALGS)
Patients 3 months of age and older with progressive familial intrahepatic cholestasis (PFIC)
Limitation of Use:
Bylvay may not be effective in a subgroup of PFIC type 2 patients with specific ABCB11 variants resulting in non-functional or complete absence of the bile salt export pump protein

Please see full Prescribing Information.

IMPORTANT SAFETY INFORMATION AND INDICATIONS

IMPORTANT SAFETY INFORMATION

Speak with your healthcare provider if you experience abdominal pain, vomiting, diarrhea, hematoma, decreased weight, or dehydration as these have been reported with the use of Bylvay. Patients should contact their healthcare provider if they experience new onset or worsening of diarrhea
Elevations in liver tests (for example, AST, ALT, TB) have been observed with use of Bylvay. The patient’s healthcare provider will obtain liver tests before starting Bylvay and periodically during treatment with Bylvay. Patients should report to their healthcare provider any symptoms of liver problems (for example, nausea, vomiting, skin or the whites of eyes turn yellow, dark or brown urine, pain on the right side of the abdomen, loss of appetite)
Bylvay may impair absorption of fat-soluble vitamins (FSV), which include vitamins A, D, E and K (vitamin K is assessed by measuring INR). The patient’s healthcare provider will obtain serum levels of vitamins A, D, E, and INR (for vitamin K) at baseline and periodically during treatment to assess for worsening of FSV deficiency
Do not swallow the 200 mcg or 600 mcg capsule(s) containing Oral Pellets whole. These are intended to be opened and the contents mixed into soft food. Take Bylvay in the morning with a meal
For patients taking bile acid binding resins, take Bylvay at least 4 hours before or 4 hours after taking a bile acid binding resin
There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to Bylvay during pregnancy. For more information, please call 1-855-252-4736

Indications and Usage

Bylvay is an ileal bile acid transporter (IBAT) inhibitor indicated for the treatment of cholestatic pruritus in:

Patients 12 months of age and older with Alagille syndrome (ALGS)
Patients 3 months of age and older with progressive familial intrahepatic cholestasis (PFIC)
Limitation of Use:
Bylvay may not be effective in a subgroup of PFIC type 2 patients with specific ABCB11 variants resulting in non-functional or complete absence of the bile salt export pump protein

Please see full Prescribing Information.

Support & Resources

Support and Resources for Families Living with PFIC

Financial & Insurance Assistance

Learn more about the Copay Assistance Program from your Care Coordinator.

Patient Assistance Program

Learn more about the Patient Assistance Program from your Care Coordinator.

Dedicated, Live Support

Care Logistics

Educational Materials & Programs

Online Resources

Additional Resources

Bylvay Instructions for Use Videos

Getting Started

IMPORTANT SAFETY INFORMATION AND INDICATIONS

IMPORTANT SAFETY INFORMATION

Indications and Usage

IMPORTANT SAFETY INFORMATION AND INDICATIONS

IMPORTANT SAFETY INFORMATION

Indications and Usage