Taking Bylvay
Easy to add Bylvay to your morning routine
Once-daily dose
Just take Bylvay with your first meal of the day.
Just take Bylvay with your first meal of the day.
Can be taken with a morning meal
No need to delay feeding or mealtimes after dosing—take Bylvay on a regular feeding schedule.
No need to delay feeding or mealtimes after dosing—take Bylvay on a regular feeding schedule.
If you are prescribed a bile acid binding resin (for example, cholestyramine, colestipol), Bylvay should be taken at least 4 hours before or 4 hours after.
Flexible, once-daily dosing to meet your needs
There are options when taking Bylvay to make things easier for patients and caregivers.
Bylvay can be taken 3 ways with 2 oral formulation options
Oral Pellets For patients weighing <19.5 kg
200 mcg
600 mcg
Pills are not actual size.
Pills are not actual size.
Should not be swallowed whole
Shells can be opened and mixed with food*
Shells can be opened and mixed with liquids†
Capsules For patients weighing ≥19.5 kg
400 mcg
1200 mcg
Pills are not actual size.
Pills are not actual size.
Can be swallowed whole
Capsules can be opened and mixed with food*
Capsules can be opened and mixed with liquids†
After mixing Bylvay with food or liquids, discard the empty shells.
*Mix Bylvay in a small amount of soft food (up to 2 tablespoons [30 mL]), such as apple sauce, oatmeal, banana or carrot puree, chocolate or rice pudding, in a bowl.
†Add 1 teaspoon (5 mL) of an age-appropriate liquid (for example, breast milk, infant formula, or water).
Doctors will determine the right dose for you or your child based on weight.
How to open Bylvay Oral Pellets and mix with food
Watch this video to learn how to open Bylvay Oral Pellets and mix them with a small amount of soft food.
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Give Bylvay with the first morning meal. Place a small amount (up to 2 tablespoons [30 mL]) of soft food (apple sauce, oatmeal, banana or carrot puree, chocolate or rice pudding) in a bowl. Keep the soft food at, or cooler than, room temperature. Note: This small amount of soft food should be less than what your child would normally eat.
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Figure A
Hold the shell containing Oral Pellets horizontally on both ends, twist in opposite directions and pull apart (see Figure A).
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Figure B
Empty the Oral Pellets into the bowl of soft food (see Figure B).
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Figure C
Gently tap the shell containing Oral Pellets to make sure that all pellets come out (see Figure C).
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If the dose requires more than 1 shell of Oral Pellets, repeat Step 2 through Step 4.
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Figure D
Gently mix the Oral Pellets with a spoon into the soft food. Note that the Oral Pellets will not dissolve (see Figure D).
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Give the entire dose right away after mixing. Do not store the Bylvay mixture for later use.
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Give water or an age-appropriate liquid, such as breast milk or infant formula, after the dose is taken.
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Dispose of (throw away) the empty Oral Pellets shells in the trash.
How to open Bylvay Oral Pellets and mix with liquid
Watch this video to learn how to open Bylvay Oral Pellets and mix them with liquid.
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Give Bylvay with the first morning meal.
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Figure A
Hold the shell containing the Oral Pellets horizontally on both ends, twist in opposite directions and pull apart (see Figure A).
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Figure E
Empty the Oral Pellets into a small mixing cup. Gently tap the shell containing Oral Pellets to ensure that all contents have been emptied into the mixing cup (see Figure E).
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If the dose requires more than 1 shell of Oral Pellets, repeat Step 2 and Step 3.
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Add 1 teaspoon (5 mL) of an age-appropriate liquid (for example, breast milk, infant formula, or water).
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Let the pellets sit in the liquid for about 5 minutes to allow complete wetting. REMINDER: The Oral Pellets will not dissolve in the liquid.
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After 5 minutes, place the tip of the oral syringe completely into the mixing cup. Pull the plunger of the syringe up slowly to withdraw the liquid and pellet mixture into the syringe. Gently push the plunger down again to expel the liquid and pellet mixture back into the mixing cup. Do this 2 to 3 times to ensure complete mixing of the pellets into the liquid.
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Figure F
Withdraw the entire contents into the syringe by pulling the plunger on the end of the syringe (see Figure F).
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Figure G
Place the tip of the syringe into the front of the child’s mouth between the tongue and the side of the mouth, and then gently push the plunger down to squirt the liquid and pellet mixture between the tongue and the side of the mouth. Do not squirt the liquid and pellet mixture in the back of the throat because this could cause gagging or choking
(see Figure G) . -
Do not give using a bottle or “sippy cup” because the Oral Pellets will not pass through the opening. The Oral Pellets will not dissolve in liquid.
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Give water or an age-appropriate liquid such as breast milk or infant formula after the dose is taken.
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Repeat Steps 8 and 9 until the entire dose has been given.
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Check to make sure all of the liquid and pellet mixture has been swallowed.
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Dispose of (throw away) the empty Oral Pellets shells in the trash.
How to take Bylvay Capsules
- Do not crush or chew Capsules
- Swallow the Capsule whole with a glass of water
- Alternatively, for patients unable to swallow the Capsules whole, Bylvay Capsules may be opened and then sprinkled and mixed with a small amount of soft food or age-appropriate liquid. Follow directions above for Oral Pellets to prepare and administer such a mixture